Cambridge Healthtech Institute’s Second Annual

Peptide Discovery and Delivery

Developing the Next Generation of Targeted Peptide Therapeutics

March 26-27, 2018 | Boston Marriott Cambridge | Cambridge, MA

CHI’s Peptide Discovery and Delivery conference reveals the latest strategies at the forefront of peptide discovery, chemistry and delivery with in-depth sessions on new chemistries, novel delivery mechanisms and the most important preclinical and clinical updates, helping you develop the next-generation of peptides therapeutics, including latest developments in antimicrobial peptides, peptide vaccines and macrocyclic and constrained peptides.

Preliminary Agenda


New Peptide Discoveries and Chemistries

KEYNOTE PRESENTATION: Peptide Drug Hunter: An Extraordinary Trek into Intracellular Target Space

Tomi Sawyer, Ph.D., Distinguished Scientist, Discovery Chemistry Modalities, Merck Research Laboratories

Engineering Potent NaV1.7 Inhibitory Peptide-Antibody Conjugates

Justin Murray, Ph.D., Senior Scientist, Hybrid Modality Engineering, Amgen

Presentation to be Confirmed

Thomas Kruse, Ph.D., Senior Principal Scientist, Novo Nordisk

Novel Peptide Therapeutics for Alzheimer's Disease

Nazneen Dewji, Ph.D., President and CEO, Cenna Biosciences, Inc.

Genetic Encoded Peptide Libraries, 48 Hours Hits Identification

Ratmir Derda, Ph.D., Assistant Professor, University of Alberta

Nanofitin-Drug Conjugates for Solid Tumors: From Imaging to Treatment

Olivier Kitten, Ph.D., Founder & CEO, Affilogic


Macrocyclic and Constrained Peptides

Properties of Orally Bioavailable Peptide Macrocycles beyond the Rule of 5

Alan Mathiowetz, Ph.D., Director, Computational Chemistry, Pfizer

Discovery and Development of Novel Macrocycle Drugs: Outer Membrane Protein Targeting Antibiotics (OMPTA), a New Class with a Novel Mode of Action

Daniel Obrecht, Ph.D., CSO & Co-Founder, Pharma, Polyphor Ltd.

Presentation to be Confirmed

David Spellmeyer, Ph.D., CSO, Circle Pharma

Cell Penetration Profiling for Biotherapeutics

Joshua Kritzer, Ph.D., Associate Professor, Department of Chemistry, Tufts University


Antimicrobial Peptides

  • Peptides as alternatives to antibiotics
  • Glycosylation of antimicrobial peptides

Stalking Elusive Pathogenic Bacteria with Cationic Amphiphilic Polyproline Helices: Diving into Human Cells to Treat Infections

Jean Chmielewski, Ph.D., AW Kramer Distinguished Professor, Department of Chemistry, Purdue University

Role of Soluble Oligomers in Antimicrobial Peptide Activities - Lessons from the Aβ Peptide of Alzheimer’s Disease

Robert D. Moir, Ph.D., Assistant Professor in Neurology, Harvard Medical School


Clinical Updates

Setmelanotide for the Treatment of Severe Obesity Resulting from MC4-Pathway Deficiency

Lex van Der Ploeg, Ph.D., CSO, Rhythm Pharmaceuticals

Development Strategies of Neo-Antigen-Based Personalized Cancer Vaccines

Jesse Dong, Ph.D., Vice President, Peptide Chemistry, Neon Therapeutics


Formulation, Stability and Delivery

How Can Nanosystems Help Address Present and Future Challenges in Peptide Delivery

Joël Richard, Ph.D., Senior Vice President, Peptides Development, Ipsen

Update on Xeris Peptide Development and Delivery

Steve Prezstelski, Ph.D., CSO, Xeris Pharmaceuticals

Presentation to be Confirmed

Pernille Tofteng Shelton, Ph.D., Senior Scientist, Medicinal Chemistry, Zealand Pharma


Analysis, CMC and Manufacturing

CMC Strategies in Preparation for Commercialization

Dave Garman, Ph.D., CTO, NoNO, Inc.




For more details on the conference, please contact:
Daniel Barry
Senior Conference Director
Cambridge Healthtech Institute
T: (+1) 781-247-6266
E: dbarry@healthtech.com

For partnering and sponsorship information, please contact:
Carolyn Benton
Manager, Business Development
Cambridge Healthtech Institute
T: (+1) 781-972-5412
E: cbenton@healthtech.com