MARCH 17 - 18, 2027
MARCH 18 - 19, 2027
Welcome to OPT Congress
OPT Congress is where the oligonucleotide and RNA communities come together to share the science, technologies, and strategies advancing the next generation of nucleic acid therapeutics. Spanning discovery through clinical development and manufacturing, the program features four focused conference tracks, expert-led short courses, and scientific discussions on therapeutic design, targeted delivery, CMC, manufacturing, emerging modalities, AI-enabled innovation, and translational research. Whether you're advancing a new modality or optimizing an established platform, OPT Congress delivers practical insights you can apply throughout the development lifecycle.
Marvin Caruthers, PhDDistinguished Professor, University of Colorado
Mano Manoharan, PhDSenior Vice President, Drug Discovery, Alnylam Pharmaceuticals
Laura Sepp-Lorenzino, PhDBiotech Executive, Board Member, Advisor, former CSO of Intellia Therapeutics, Inc.
David Corey, PhDProfessor, Department of Pharmacology, UT Southwestern
Chandra Vargeese, PhDCTO & Head, Platform Delivery Sciences, Wave Life Sciences
Dmitry Samarsky, PhDCSO and Board Member, GALconda Therapeutics
Paloma Giangrande, PhDPresident & Founder Biologic Insights LLC; CSO & Founder, Program Therapeutics Inc.
Ekkehard Leberer, PhDSenior Life Sciences Consultant, ELBIOCON
Connect with scientists and decision-makers developing the next generation of oligonucleotide and RNA therapeutics
Explore sponsorship and exhibit opportunities to showcase your technologies, build strategic partnerships, and engage with an audience actively advancing therapeutic innovation.
Stay Ahead of Emerging Science and Technologies Advancing Next Generation Nucleic Acids
Four Conferences, One Pass
With our all-access pass, move freely across discovery, manufacturing, conjugates and emerging modalities
Learn from 70+ Experts
Gain insights from world-renowned industry leaders and academics as they share the lates breakthroughs
Network with 300+ Peers
Connect with leading scientists, executive directors, regulatory strategists, formulation experts, and business development leaders
In-Depth Short Courses
Join expert-led courses that offer practical frameworks, strategies, and insights from safety and toxicity to regulatory submissions
“There are tremendous opportunities here that have yet to be exploited in this field, and people who want to do good science can make some great discoveries.”
David Corey, PhD
Professor, Department of Pharmacology, UT Southwestern
“Valuable insights for newbies and pros into the field of oligos and peptides.”
Andreas Reindl
COO, Allozymes
“What I really like about this conference, is it brings together people that span the whole cycle from discovery all the way to manufacturing and commercialization. We get to interact, we get to discuss, and see how they field continues to evolve.”
Laura Sepp-Lorenzino, PhD
Biotech Executive, former CSO of Intellia Therapeutics, Inc
“Attending the OPT Congress for the first time gave me a clear sense of why people return: the quality of the science and the welcoming community.”
Terry Moore
Professor, University of Illinois Chicago