Cambridge Healthtech Institute’s 3rd Annual

mRNA Design & Delivery

Increased Efficacy, Better Stability, Targeted Delivery, and Improved Safety

March 11-12, 2025

In recent years, developing messenger RNA (mRNA) as a drug for treating diseases like cancer, rare genetic disorders, and autoimmunity has certainly gained significant momentum. However, has the understanding of mRNA biology and the chemical modifications and delivery technologies needed to address the existing translational challenges kept pace with the growing interest? Cambridge Healthtech Institute’s conference on mRNA Design & Delivery highlights the developments that are underway to design and deliver mRNA to make it efficacious, safe, and targeted for treating diverse disease indications.

Coverage will include, but is not limited to:

Chemical modifications for improving mRNA efficacy and stability
Understanding mRNA biology and function leading to better drug design
New techniques for probing mRNA secondary structure, folding, and binding
Using AI/machine learning tools for structure-activity predictions
Exploring ways for enhancing mRNA upregulation
Formulations and vehicles for targeted tissue and cell-type specific mRNA delivery
Understanding PK/PD, bioavailability, and dosing regimens for mRNA drugs

The deadline for priority consideration is August 23^rd, 2024.

All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.

Opportunities for Participation: