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Pre-conference Short Courses | Tuesday, March 18 | In-Person Only

Short Course 1: Safety & Toxicity of Nucleic Acids
Short Course 2: Successful Late Phase Regulatory Submission for a Complex Oligonucleotide
Short Course 3: Next-Gend ADCs & Advanced Linkers & Conjugates: Mastering Design Linker Optimization & Stability

Welcome to OPT Congress:
Oligonucleotide, mRNA & Peptide Therapeutics

OPT Congress 2026 is the leading industry event for scientists, directors, and technology providers driving innovation across oligonucleotide, mRNA, and peptide therapeutics. Now in its 11th year, this event provides a unique forum for translating cutting-edge science into transformative medicines, with expanded 2026 programming that includes the brand-new Peptides & Emerging Drug Conjugates conference. This year’s agenda brings together experts from discovery through development, with dedicated content spanning AI-enabled design, extrahepatic delivery, scalable manufacturing, and next-gen modalities including saRNA, circular RNA, and radioligand peptide conjugates.

Across four focused conferences —Oligonucleotide Discovery & Delivery, CMC & Manufacturing, mRNA & Emerging Modalities, and Peptides & Emerging Conjugates—attendees will explore 60+ scientific presentations, collaborative case studies, and real-world implementation strategies. From novel linkers and chemistries to regulatory insights, tech transfer, and delivery breakthroughs, OPT Congress fosters dialogue between pharma, biotech, academia, and technology providers. Join us for two days of actionable insights, short courses, and customizable content designed to support your therapeutic programs from bench to bedside.

 

Event Highlights and Testimonials Video
Sponsor and Exhibit
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4 Conferences
60+ Speakers
300+ Attendees
150+ Unique Organizations
Short Courses

2026 Plenary Keynote Speakers

Timothy Yu, PhD

Timothy Yu, PhD
Associate Professor Pediatrics, Genetics & Genomics, Boston Children’s Hospital

Brenda Bass, PhD

Brenda Bass, PhD
Distinguished Professor, Biochemistry, University of Utah

Debra Miller

Debra Miller
Founder & CEO, CureDuchenne

Weimin Wang, PhD

Weimin Wang, PhD
Founder & CEO, Sanegene Bio

Our Executive Advisory Board

Marvin Caruthers, PhD
Distinguished Professor, University of Colorado

Mano Manoharan, PhD
Senior Vice President, Drug Discovery, Alnylam Pharmaceuticals

Chandra Vargeese, PhD
CTO & Head, Platform Delivery Sciences, Wave Life Sciences

Dmitry Samarsky, PhD
CSO and Board Member, GALconda Therapeutics

Arthur Levin, PhD
Board of Directors, Avidity Biosciences

Paloma Giangrande, PhD
Senior Vice President, Discovery and Translational Biology, Orbital Therapeutics

Lubo Nechev, PhD
Vice President Process and Analytical Sciences, Alnylam Pharmaceuticals

Ekkehard Leberer, PhD
Senior Life Sciences Consultant, ELBIOCON